A computational model for cortical spreading depression

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Summary
We propose a new computational model for migraine-related cortical spreading depression (CSD) by using a neural field framework. The model is extended from the Wilson-Cowan-Amari formalism [1, 2]. It is based on an excitatory-inhibitory neuronal population pair which is coupled to a potassium concentration variable. This model is spatially extended to a cortical layer patch. Therefore, it can model both the ignition and propagation of CSD.
Abstract ID :
106

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